HYPOLIPIDEMIC THERAPY IN PATIENTS AFTER HEART TRANSPLANTATION: STATINS
نویسندگان
چکیده
منابع مشابه
The role of statins in patients after heart transplantation
Numerous studies have shown that statin therapy initiated early after heart transplantation improves the short- and long-term prognosis, leading to a reduction in the incidence of cardiac allograft vasculopathy (CAV), acute rejection episodes and significantly lowers the incidence of cancer in this patient population. The molecular mechanisms responsible for the beneficial effects of statins in...
متن کاملStatins and the Risk of Cancer after Heart Transplantation
Background—Although newer immunosuppressive agents, such as mTOR (mammalian target of rapamycin) inhibitors, have lowered the occurrence of malignancies after transplantation, cancer is still a leading cause of death late after heart transplantation. Statins may have an impact on clinical outcomes beyond their lipid-lowering effects. The aim of the present study was to delineate whether statin ...
متن کاملShould all patients receive statins to reduce cancer risk after heart transplantation?
The study by Frolich et al1 in this issue of Circulation adds to the body of evidence that statins as a class of drugs have effects that reduce the chance of cancer initiation and progression, recapitulating findings showing reductions in cancer-related mortality in statin users in other major malignancies such as breast and prostate cancer.2,3 The authors are explicit in recognizing the flaws ...
متن کاملEffects of vildagliptin (Galvus®) therapy in patients with type 2 diabetes mellitus after heart transplantation
BACKGROUND Type 2 Diabetes mellitus (T2DM) is a common comorbidity in patients after heart transplantation (HTx) and is associated with adverse long-term outcomes. METHODS The retrospective study reported here analyzed the effects of vildagliptin therapy in stable patients post-HTx with T2DM and compared these with control patients for matched-pairs analysis. A total of 30 stable patients pos...
متن کاملAnalysis of malignancies in patients after heart transplantation with subsequent immunosuppressive therapy
OBJECTIVE The aim of this study was to analyze the distribution of malignancies in patients after heart transplantation (HTX) and to evaluate the risk factors including immunosuppressive therapy with regard to the development of malignancies and survival. Special emphasis was placed on the effects of a mammalian target of rapamycin (mTOR) containing immunosuppressive regimen. METHODS A total ...
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ژورنال
عنوان ژورنال: Russian Journal of Transplantology and Artificial Organs
سال: 2016
ISSN: 2412-6160,1995-1191
DOI: 10.15825/1995-1191-2016-2-171-176